Quoting Clinical Applications Of Passionflower

Passionflower is useful for anxiety, mild depression, high blood pressure, and generalized pain. It can be used to treat insomnia, especially that which is characterized by racing thoughts before bedtime.

Passionflower is most commonly used in combination with other herbs, as a way to address any stress or anxiety that may be associated with the condition being treated.

Cautions & Safety Information

May potentiate the effects of sedatives including barbiturates and benzodiazepines. May potentiate the effects of SSRI and SNRI medications.

Passiflora spp. is classified by the FDA as “generally regarded as safe”. To study the toxicity of this plant, researchers tested an ethanol leaf extract of Passiflora feotida, that was given to mice in doses of 2000 mg/kg with no mortality and no alteration in behavior .

There may be an Interaction with barbiturates, benzodiazepines with Passiflora spp. There is a possibility for it to potentiate its effects, caution should be used as it may increase sedation. This effect may actually be beneficial but needs more clinical study.

Synergy With Other herbs & Nutrients

Commonly combined with such herbs as valerian, hops, st. john’s wort, and lemon balm.
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